The Benefits of Psilocybin on Depression 

A few kinds of psychedelic medications, like psilocybin and ecstasy, have shown promise as treatments for depression and post-traumatic stress that are resistant to treatment. They seem to work by ensuring the development of new connections between brain neurons. The ability of the cerebrum to make new connections is known as plasticity.

How Does Psilocybin Function ?

Psilocybin is generally created in over 200 species of basidiomycetes organisms, a phylum of filamentous fungi collectively called psilocybin mushrooms. These mushrooms are in all shapes and sizes. They are found across the world. Also, psilocybin can be artificially produced and taken in standardized doses, often utilized in clinical settings.

Psilocybin is a class of serotonergic hallucinogenics that integrates LSD and mescaline. Depending on the individual and dosage, psilocybin can prompt euphoria, changes in discernment, perceived spiritual encounters, and sensations of detachment, among other impacts.

The effects are not because of psilocybin itself, but upon ingestion, it produces psilocin, a dynamic compound. Psilocin activates serotonin 5-HT2a receptors on cortical pyramidal cells in the frontal cortex(brain).

Advantages of Psilocybin Treatment

Psilocybin treatment has several benefits. It’s effective for tackling mental health issues. With regards to treating depression, experts highlighted psilocybin’s speed and viability as 2 of its most appealing characteristics.

The effects of psilocybin are noticeable as soon as it’s used (after a few days) compared with standard antidepressants, which, when they work, can require some weeks to completely kick in. The stimulant impacts can likewise keep going for some time, from 4 weeks up to 6 months to a year, depending on the study.

While someone could need to take a standard SSRI every day for months or years, they could get only a dose of psilocybin at regular intervals or just once per year. The “transdiagnostic” nature of psilocybin (for instance, the ability to be utilized for various indicators) is an added advantage.


Psilocybin has been successfully used along with other medications to enhance good health. This substance is also effective for the treatment of depression. However, more studies are needed for future use. You can attend Tangerine Retreat to learn more about psilocybin treatment.

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